Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin

Methionine enkephalin (MENK) protected macrophages from ferroptosis by downregulating HMOX1 and ferritin

Abstract Objective The aim of this work was to investigate the immunological effect of MENK by analyzing the protein spectrum and bioinformatics of macrophage RAW264.7, and to explore the relationship between macrophage and ferroptosis. Result We employed proteomic analysis to identify differentiall...

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Bibliographic Details
Main Authors: Jing Tian, Wenrui Fu, Zifeng Xie, Yuanlong Zhao, Haochen Yang, Jiafan Zhao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Proteome Science
Subjects:
MENK
Macrophage
Proteomics analysis
Ferroptosis
Iron metabolism
Online Access:https://doi.org/10.1186/s12953-024-00228-x

Internet

https://doi.org/10.1186/s12953-024-00228-x

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