<i>Blautia coccoides</i> JCM1395<sup>T</sup> Achieved Intratumoral Growth with Minimal Inflammation: Evidence for Live Bacterial Therapeutic Potential by an Optimized Sample Preparation and Colony PCR Method

<i>Blautia coccoides</i> JCM1395<sup>T</sup> Achieved Intratumoral Growth with Minimal Inflammation: Evidence for Live Bacterial Therapeutic Potential by an Optimized Sample Preparation and Colony PCR Method

We demonstrate that <i>Blautia coccoides</i> JCM1395<sup>T</sup> has the potential to be used for tumor-targeted live bacterial therapeutics. Prior to studying its in vivo biodistribution, a sample preparation method for reliable quantitative analysis of bacteria in biologica...

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Bibliographic Details
Main Authors: Shoko Nomura, Erike W. Sukowati, Yuko Shigeno, Maiko Takahashi, Akari Kato, Yoshimi Benno, Fumiyoshi Yamashita, Hidefumi Mukai
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceutics
Subjects:
bacteria
bacterial cancer therapy
colony PCR
16S rRNA genes
<i>Blautia coccoides</i>
Online Access:https://www.mdpi.com/1999-4923/15/3/989

Internet

https://www.mdpi.com/1999-4923/15/3/989

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