Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1

Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1

Long non-coding RNA antisense non-coding RNA in the INK4 locus (ANRIL) has been reported to promote tumorigenesis via regulating microRNA (miR)-99a in gastric cancer cells. However, the role of each component involved in it is still not well understood. This study aimed to verify the role of ANRIL i...

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Bibliographic Details
Main Authors: Pei Liu, Mingming Zhang, Qinghui Niu, Fengjuan Zhang, Yuling Yang, Xiangjun Jiang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Gastric cancer
lncRNA ANRIL
miR-99a
BMI1
Apoptotic pathway
Notch/mTOR pathway
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000609&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000609&lng=en&tlng=en

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