Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1

Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1

Long non-coding RNA antisense non-coding RNA in the INK4 locus (ANRIL) has been reported to promote tumorigenesis via regulating microRNA (miR)-99a in gastric cancer cells. However, the role of each component involved in it is still not well understood. This study aimed to verify the role of ANRIL i...

Full description

Bibliographic Details
Main Authors:	Pei Liu, Mingming Zhang, Qinghui Niu, Fengjuan Zhang, Yuling Yang, Xiangjun Jiang
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2018-08-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Gastric cancer lncRNA ANRIL miR-99a BMI1 Apoptotic pathway Notch/mTOR pathway
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000609&lng=en&tlng=en

Similar Items

Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in <i>TP53</i> or <i>PTEN</i> Tumor Suppressors
by: Aleksandra Ellert-Miklaszewska, et al.
Published: (2021-01-01)

Lnc‐ANRIL modulates the immune response associated with NF‐κB pathway in LPS‐stimulated bovine mammary epithelial cells
by: Jinye Lu, et al.
Published: (2023-12-01)

Integrated bioinformatics analysis for the identification of hub genes and signaling pathways related to circANRIL
by: Qiuyan Qin, et al.
Published: (2022-04-01)

Oxidative Stress and Apoptotic Responses Elicited by <i>Nostoc</i>-Synthesized Silver Nanoparticles against Different Cancer Cell Lines
by: Reham Samir Hamida, et al.
Published: (2020-07-01)

The role of long non-coding RNA ANRIL in the development of atherosclerosis
by: Ilgiz Gareev, et al.
Published: (2022-12-01)

The Long Non-Coding RNA ANRIL in Cancers
by: Aymeric Sanchez, et al.
Published: (2023-08-01)

Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients
by: A. Arbiol-Roca, et al.
Published: (2017-04-01)

MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma
by: Cui Li, et al.
Published: (2012-11-01)

Construction of a ceRNA Network Related to Rheumatoid Arthritis
by: Zhanya Huang, et al.
Published: (2022-04-01)

Long Non-coding RNA ANRIL in the Nucleus Associates With Periostin Expression in Breast Cancer
by: Paulomi M. Mehta-Mujoo, et al.
Published: (2019-09-01)

Clinical Implications of mTOR Expression in Papillary Thyroid Cancer—A Systematic Review
by: Aleksandra Derwich, et al.
Published: (2023-03-01)

The lncRNA ANRIL Gene rs2151280 GG Genotype is Associated with Increased Susceptibility to Recurrent Miscarriage in a Southern Chinese Population
by: Che D, et al.
Published: (2021-06-01)

LncRNA ANRIL regulates AML development through modulating the glucose metabolism pathway of AdipoR1/AMPK/SIRT1
by: Lin-Yu Sun, et al.
Published: (2018-08-01)

Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191
by: Deyu Huang, et al.
Published: (2018-09-01)

Serum lncRNA-ANRIL and SOX9 expression levels in glioma patients and their relationship with poor prognosis
by: Youlu Sun, et al.
Published: (2021-09-01)

LncRNA ANRIL/miR-7-5p/TCF4 axis contributes to the progression of T cell acute lymphoblastic leukemia
by: Gang Li, et al.
Published: (2020-07-01)

Kinase Inhibitors in Genetic Diseases
by: Lucia D’Antona, et al.
Published: (2023-03-01)

Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway
by: Xin Wu, et al.
Published: (2020-11-01)

Long non-coding RNA ANRIL-mediated inflammation response is involved in protective effect of rhein in uric acid nephropathy rats
by: Jiacai Hu, et al.
Published: (2019-01-01)

Alteration in the mRNA expression profile of the autophagy-related mTOR pathway in schizophrenia patients treated with olanzapine
by: Fengwei Cui, et al.
Published: (2021-08-01)

Advances in the mTOR signaling pathway and its inhibitor rapamycin in epilepsy
by: Wei Zhao, et al.
Published: (2023-06-01)

CHANGE OF THE MTOR PATHWAY IN TISSUES OF OVERFED GEESE
by: C Han, et al.
Published: (2015-09-01)

Quercetin Can Improve Spinal Cord Injury by Regulating the mTOR Signaling Pathway
by: Xichen Wang, et al.
Published: (2022-05-01)

Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters
by: Yao Hu, et al.

mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
by: Zhilin Zou, et al.
Published: (2020-03-01)

HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway
by: Xinyu Wang, et al.
Published: (2020-09-01)

The microRNA 132 Regulates Fluid Shear Stress-Induced Differentiation in Periodontal Ligament Cells through mTOR Signaling Pathway
by: Lin Qi, et al.
Published: (2014-02-01)

Acute knockdown of Depdc5 leads to synaptic defects in mTOR-related epileptogenesis
by: Antonio De Fusco, et al.
Published: (2020-06-01)

PTEN/AKT/mTOR pathway involvement in autophagy, mediated by miR-99a-3p and energy metabolism in ammonia-exposed chicken bursal lymphocytes
by: Syed Waqas Ali Shah, et al.
Published: (2021-02-01)

ANRIL: A lncRNA at the CDKN2A/B Locus With Roles in Cancer and Metabolic Disease
by: Yahui Kong, et al.
Published: (2018-07-01)

Genetic and epigenetic associations of ANRIL with coronary artery disease and risk factors
by: Bayi Xu, et al.
Published: (2021-10-01)

microRNA-99a Restricts Replication of Hepatitis C Virus by Targeting mTOR and De Novo Lipogenesis
by: Eun Byul Lee, et al.
Published: (2020-06-01)

Silencing circular ANRIL protects HK-2 cells from lipopolysaccharide-induced inflammatory injury through up-regulating microRNA-9
by: Wenyan Deng, et al.
Published: (2019-12-01)

Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study
by: Jiantao Liu, et al.
Published: (2023-12-01)

Exploratory Analysis of Selected Components of the mTOR Pathway Reveals Potentially Crucial Associations with Childhood Malnutrition
by: Parag Palit, et al.
Published: (2022-04-01)

Targeting mTOR Signaling by Dietary Polyphenols in Obesity Prevention
by: Yunyun Cao, et al.
Published: (2022-12-01)

The Effect of Dietary Lipid Supplementation on the Serum Biochemistry, Antioxidant Responses, Initial Immunity, and mTOR Pathway of Juvenile Tilapia (<i>Oreochromis niloticus</i>)
by: Yongqiang Liu, et al.
Published: (2023-10-01)

Metformin as a Treatment Strategy for Sjögren’s Syndrome
by: Joa Kim, et al.
Published: (2021-07-01)

Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion
by: Marie Marotel, et al.
Published: (2021-01-01)

mTOR pathway gene mutations predict response to immune checkpoint inhibitors in multiple cancers
by: Lei Cheng, et al.
Published: (2022-05-01)