Two loci on chromosome 5 are associated with serum IgE levels in Labrador retrievers.

Two loci on chromosome 5 are associated with serum IgE levels in Labrador retrievers.

Crosslinking of immunoglobulin E antibodies (IgE) bound at the surface of mast cells and subsequent mediator release is considered the most important trigger for allergic reactions. Therefore, the genetic control of IgE levels is studied in the context of allergic diseases, such as asthma, atopic rh...

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Main Authors: Marta Owczarek-Lipska, Béatrice Lauber, Vivianne Molitor, Sabrina Meury, Marcin Kierczak, Katarina Tengvall, Matthew T Webster, Vidhya Jagannathan, Yvette Schlotter, Ton Willemse, Anke Hendricks, Kerstin Bergvall, Ake Hedhammar, Göran Andersson, Kerstin Lindblad-Toh, Claude Favrot, Petra Roosje, Eliane Marti, Tosso Leeb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3376118?pdf=render

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http://europepmc.org/articles/PMC3376118?pdf=render

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