PDE5 inhibitor drugs for use in dementia

Abstract Alzheimer's disease and related dementias (ADRD) remain a major health‐care challenge with few licensed medications. Repurposing existing drugs may afford prevention and treatment. Phosphodiesterase‐5 (PDE5) is widely expressed in vascular myocytes, neurons, and glia. Potent, selective...

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Bibliographic Details
Main Authors: Atticus H. Hainsworth, Ottavio Arancio, Fanny M. Elahi, Jeremy D. Isaacs, Feixiong Cheng
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Online Access:https://doi.org/10.1002/trc2.12412