A genetic variant in the promoter region of miR-106b-25 cluster and risk of HBV infection and hepatocellular carcinoma.

A genetic variant in the promoter region of miR-106b-25 cluster and risk of HBV infection and hepatocellular carcinoma.

BACKGROUND: MiR-106b-25 cluster, hosted in intron 13 of MCM7, may play integral roles in diverse processes including immune response and tumorigenesis. A single nucleotide polymorphism (SNP), rs999885, is located in the promoter region of MCM7. METHODS: We performed a case-control study including 13...

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Bibliographic Details
Main Authors: Yao Liu, Yixin Zhang, Juan Wen, Li Liu, Xiangjun Zhai, Jibin Liu, Shandong Pan, Jianguo Chen, Hongbing Shen, Zhibin Hu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290543?pdf=render

Internet

http://europepmc.org/articles/PMC3290543?pdf=render

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