The use of denosumab in the setting of acute pathological fracture through giant cell tumour of bone

Abstract Background Denosumab (XgevaTM) is a fully human antibody to RANK-Ligand, an important signal mediator in the pathogenesis of giant cell tumour of bone (GCTB). The use of denosumab in the treatment of GCTB has changed the way in which these tumours are managed over the past years. Case prese...

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Bibliographic Details
Main Authors: Wolfram Weschenfelder, John M. Abrahams, Luke J. Johnson
Format: Article
Language:English
Published: BMC 2021-02-01
Series:World Journal of Surgical Oncology
Subjects:
Online Access:https://doi.org/10.1186/s12957-021-02143-3