Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy

Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy

Abstract Background Neuronal dysfunction and degeneration linked to α-synuclein (αS) pathology is thought to be responsible for the progressive nature of Parkinson’s disease and related dementia with Lewy bodies. Studies have indicated bidirectional pathological relationships between αS pathology an...

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Bibliographic Details
Main Authors: Scott C. Vermilyea, Anne Christensen, Joyce Meints, Balvindar Singh, Héctor Martell-Martínez, Md. Razaul Karim, Michael K. Lee
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Translational Neurodegeneration
Subjects:
α-Synuclein
Tau
Parkinson’s disease
Lewy body disease
Neurodegeneration
Online Access:https://doi.org/10.1186/s40035-022-00309-x

Internet

https://doi.org/10.1186/s40035-022-00309-x

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