Synthesis of New Triarylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE2 and Nitric Oxide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages
This article describes the design, synthesis, and in vitro anti-inflammatory screening of new triarylpyrazole derivatives. A total of 34 new compounds were synthesized containing a terminal arylsulfonamide moiety and a different linker between the sulfonamide and pyridine ring at position 4 of the p...
Main Authors: | Mohammed S. Abdel-Maksoud, Mohammed I. El-Gamal, Mahmoud M. Gamal El-Din, Yunji Choi, Jungseung Choi, Ji-Sun Shin, Shin-Young Kang, Kyung Ho Yoo, Kyung-Tae Lee, Daejin Baek, Chang-Hyun Oh |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-10-01
|
Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/23/10/2556 |
Similar Items
-
Black pepper oil (Piper nigrum L.) mitigates dexamethasone induced pancreatic damage via modulation of oxidative and nitrosative stress
by: Mona F. Mahmoud, et al.
Published: (2022-09-01) -
Nitric oxide in kidney transplantation
by: George J. Dugbartey
Published: (2023-11-01) -
Life, death and nitric oxide /
by: 221428 Butler, Anthony R., et al.
Published: (2003) -
Nitric Oxide (NO) and NO Synthases (NOS)-Based Targeted Therapy for Colon Cancer
by: Hao Wang, et al.
Published: (2020-07-01) -
LPS-stimulated microglial cells promote ganglion cell death in organotypic cultures of quail embryo retina
by: Ana Sierra-Martín, et al.
Published: (2023-03-01)