Progress and challenges of plant-derived nucleic acids as therapeutics in macrophage-mediated RNA therapy

Plant-derived nucleic acids, especially small RNAs have been proved by increasing evidence in the pharmacological activities and disease treatment values in macrophage meditated anti-tumor performance, immune regulating functions and antiviral activities. But the uptake, application and delivery str...

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Bibliographic Details
Main Authors: Yu-Da Liu, Hao-Ran Chen, Yao Zhang, Ge Yan, Hao-Jie Yan, Qi Zhu, Li-Hua Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1255668/full