Oxidized Low‐Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles

Oxidized Low‐Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles

Background Activated vascular cells produce submicron prothrombotic and proinflammatory microparticle vesicles. Atherosclerotic plaques contain high levels of microparticles. Plasma microparticle levels increase during acute coronary syndromes and the thrombotic consequences of plaque rupture likely...

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Bibliographic Details
Main Authors: Julio F. Marchini, Andre Manica, Paulo Crestani, Jochen Dutzmann, Eduardo J. Folco, Heinz Weber, Peter Libby, Kevin Croce
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
caspase
lipids
microparticles
oxidized
signal transduction
tissue factor
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.015878

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.015878

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