Genetic Primary Microcephalies: When Centrosome Dysfunction Dictates Brain and Body Size
Primary microcephalies (PMs) are defects in brain growth that are detectable at or before birth and are responsible for neurodevelopmental disorders. Most are caused by biallelic or, more rarely, dominant mutations in one of the likely hundreds of genes encoding PM proteins, i.e., ubiquitous centros...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/12/13/1807 |