Genetic Primary Microcephalies: When Centrosome Dysfunction Dictates Brain and Body Size

Primary microcephalies (PMs) are defects in brain growth that are detectable at or before birth and are responsible for neurodevelopmental disorders. Most are caused by biallelic or, more rarely, dominant mutations in one of the likely hundreds of genes encoding PM proteins, i.e., ubiquitous centros...

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Bibliographic Details
Main Authors: Sarah Farcy, Hassina Hachour, Nadia Bahi-Buisson, Sandrine Passemard
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/13/1807