Assessment of causal effects of physical activity on the risk of osteoarthritis: a two-sample Mendelian randomization study

Abstract Background Growing evidence supports an association between physical activity (PA) and the risk of osteoarthritis (OA), but this may be influenced by confounding and reverse causality. Therefore, we performed a two-sample Mendelian randomization (MR) analysis to reveal the causal relationsh...

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Bibliographic Details
Main Authors: Bin Wang, Yang Liu, Yao-Chen Zhang, Zi-Yi Han, Jia-Lin Hou, Shuai Chen, Chuan Xiang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Medical Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12920-023-01681-x