ACO1 and IREB2 downregulation confer poor prognosis and correlate with autophagy-related ferroptosis and immune infiltration in KIRC

ACO1 and IREB2 downregulation confer poor prognosis and correlate with autophagy-related ferroptosis and immune infiltration in KIRC

BackgroundACO1 and IREB2 are two homologous cytosolic regulatory proteins, which sense iron levels and change iron metabolism–linked molecules. These two genes were noticeably decreased in kidney renal clear cell carcinoma (KIRC), which confer poor survival. Meanwhile, there is a paucity of informat...

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Bibliographic Details
Main Authors: Ting Zhu, Zhuoyu Xiao, Haoyu Yuan, Hu Tian, Taoyi Chen, Qi Chen, Mingkun Chen, Jiankun Yang, Qizhao Zhou, Wenbin Guo, Kangyi Xue, Ming Xia, Jiming Bao, Cheng Yang, Haifeng Duan, Hongyi Wang, Zhipeng Huang, Cundong Liu, Junhao Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
ACO1
IREB2
kidney renal clear cell carcinoma
ferroptosis
disease progression
tumor immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.929838/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.929838/full

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