Pathological Sequelae Associated with Skeletal Muscle Atrophy and Histopathology in G93A*SOD1 Mice

Pathological Sequelae Associated with Skeletal Muscle Atrophy and Histopathology in G93A*SOD1 Mice

Amyotrophic lateral sclerosis (ALS) is a complex systemic disease that primarily involves motor neuron dysfunction and skeletal muscle atrophy. One commonly used mouse model to study ALS was generated by transgenic expression of a mutant form of human superoxide dismutase 1 (SOD1) gene harboring a s...

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Bibliographic Details
Main Authors: Richa Aishwarya, Chowdhury S. Abdullah, Naznin Sultana Remex, Sadia Nitu, Brandon Hartman, Judy King, Mohammad Alfrad Nobel Bhuiyan, Oren Rom, Sumitra Miriyala, Manikandan Panchatcharam, A. Wayne Orr, Christopher G. Kevil, Md. Shenuarin Bhuiyan
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Muscles
Subjects:
skeletal muscle
ALS
G93A*SOD1
histopathology
mitochondria
Online Access:https://www.mdpi.com/2813-0413/2/1/6

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https://www.mdpi.com/2813-0413/2/1/6

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