Spatial variation of the gut microbiome in response to long-term metformin treatment in high-fat diet-induced type 2 diabetes mouse model of both sexes

Spatial variation of the gut microbiome in response to long-term metformin treatment in high-fat diet-induced type 2 diabetes mouse model of both sexes

ABSTRACTAntidiabetic drug metformin alters the gut microbiome composition in the context of type 2 diabetes and other diseases; however, its effects have been mainly studied using fecal samples, which offer limited information about the intestinal site-specific effects of this drug. Our study aimed...

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Bibliographic Details
Main Authors: Laila Silamiķele, Rihards Saksis, Ivars Silamiķelis, Patrīcija Paulīne Kotoviča, Monta Brīvība, Ineta Kalniņa, Zane Kalniņa, Dāvids Fridmanis, Jānis Kloviņš
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Metformin
gut microbiome
intestinal parts
lumen and mucosa
C57BL/6N
high-fat diet
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2188663

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https://www.tandfonline.com/doi/10.1080/19490976.2023.2188663

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