In silico identification of single nucleotide variations at CpG sites regulating CpG island existence and size

Abstract Genetic and epigenetic modifications of genes involved in the key regulatory pathways play a significant role in the pathophysiology and progression of multifactorial diseases. The present study is an attempt to identify single nucleotide variations (SNVs) at CpG sites of promoters of ACAT1...

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Bibliographic Details
Main Authors: Nivas Shyamala, Chaitra Lava Kongettira, Kaushik Puranam, Keerthi Kupsal, Ramanjaneyulu Kummari, Chiranjeevi Padala, Surekha Rani Hanumanth
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05198-8