KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer

KK-LC-1 as a therapeutic target to eliminate ALDH+ stem cells in triple negative breast cancer

Abstract Failure to achieve complete elimination of triple negative breast cancer (TNBC) stem cells after adjuvant therapy is associated with poor outcomes. Aldehyde dehydrogenase 1 (ALDH1) is a marker of breast cancer stem cells (BCSCs), and its enzymatic activity regulates tumor stemness. Identify...

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Bibliographic Details
Main Authors: Jiawen Bu, Yixiao Zhang, Sijin Wu, Haonan Li, Lisha Sun, Yang Liu, Xudong Zhu, Xinbo Qiao, Qingtian Ma, Chao Liu, Nan Niu, Jinqi Xue, Guanglei Chen, Yongliang Yang, Caigang Liu
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38097-1

Internet

https://doi.org/10.1038/s41467-023-38097-1

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