A Simple, Robust, and Convenient HPLC Assay for Urinary Lactulose and Mannitol in the Dual Sugar Absorption Test

Background: Heterogeneous laborious analytical methodologies for the determination of urinary lactulose and mannitol limit their utility in intestinal permeability testing. Methods: We developed an assay using a Shimadzu HPLC system, an Aminex HPX87C column, and refractive index detection. The test...

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Bibliographic Details
Main Authors: Ivana R. Sequeira, Marlena C. Kruger, Roger D. Hurst, Roger G. Lentle
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/9/2677