Treatment with the soluble guanylate cyclase activator BAY 60-2770 restores in vitro bladder contractile responses in a rat model of chronic prostatitis

Treatment with the soluble guanylate cyclase activator BAY 60-2770 restores in vitro bladder contractile responses in a rat model of chronic prostatitis

Aim:: Examine how innate bladder contractility and corresponding receptor expression was affected by chronic prostatitis (CP) and how treatment with the soluble guanylate cyclase (sGC) activator BAY 60-2770 influenced this. Methods:: To create a functional model for CP, 24 male Sprague-Dawley rats w...

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Bibliographic Details
Main Authors: Ozgu Aydogdu, Fernando Perez, Jan Rataj, Felicia Nilsson, Patrik Aronsson, Thomas Carlsson, Peter Sandner, Bhavik Patel, Gunnar Tobin, Michael Winder
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Continence
Subjects:
sGC activator
Chronic prostatitis
Urinary bladder
Organ bath
In vitro
Animal model
Online Access:http://www.sciencedirect.com/science/article/pii/S2772973722009961

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http://www.sciencedirect.com/science/article/pii/S2772973722009961

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