Cross-reactive neutralizing human monoclonal antibodies mapping to variable antigenic sites on the norovirus major capsid protein

Human noroviruses are the major viral cause of acute gastroenteritis around the world. Although norovirus symptoms are in most cases mild and self-limited, severe and prolonged symptoms can occur in the elderly and in immunocompromised individuals. Thus, there is a great need for the development of...

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Bibliographic Details
Main Authors: Lauren A. Ford-Siltz, Kentaro Tohma, Gabriela S. Alvarado, Joseph A. Kendra, Kelsey A. Pilewski, James E. Crowe, Gabriel I. Parra
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040836/full