REGULATION OF Fc RECEPTOR ENDOCYTIC TRAFFICKING BY UBIQUITINATION

Most immune cells, particularly phagocytes, express various receptors for the Fc-portion of the different immunoglobulin isotypes (Fc receptors, FcRs). By binding to the antibody, they provide a link between the adaptive immune system and the powerful effector functions triggered by innate immune ce...

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Bibliographic Details
Main Authors: Rosa eMolfetta, Linda eQuatrini, Francesca eGasparrini, Beatrice eZitti, Angela eSantoni, Rossella ePaolini
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00449/full