Synthesis, Crystal Structure and Solid State Transformation of 1,2-Bis[(1-methyl-1<i>H</i>-imidazole-2-yl)thio]ethane

Synthesis, Crystal Structure and Solid State Transformation of 1,2-Bis[(1-methyl-1<i>H</i>-imidazole-2-yl)thio]ethane

The spontaneous <i>S</i>-alkylation of the thyreostatic drug methimazole (1-methyl-1,3-dihydro-1<i>H</i>-imidazole-2-thione, <b>1</b>) with 1,2-dichloroethane at room temperature, in dark or light conditions, led to the formation of its related substance 1,2-bis[(...

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Bibliographic Details
Main Authors: Leo Štefan, Dubravka Matković-Čalogović, Darko Filić, Miljenko Dumić
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Crystals
Subjects:
methimazole
1,2-bis[(1-methyl-1<i>H</i>-imidazole-2-yl)thio]ethane
solid-state forms
hydrates
dehydration
Online Access:https://www.mdpi.com/2073-4352/10/8/667

Internet

https://www.mdpi.com/2073-4352/10/8/667

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