Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Activation of the p53 signaling pathway by piRNA-MW557525 overexpression induces a G0/G1 phase arrest thus inhibiting neuroblastoma growth

Abstract Background Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. Due to drug resistance to radiotherapy and chemotherapy, mainly due to the existence of cancer stem cells (CSCs), some children still have a poor prognosis. Therefore, researchers have focused t...

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Bibliographic Details
Main Authors: Tao Mi, Xiaojun Tan, Zhang Wang, Zhaoxia Zhang, Liming Jin, Jinkui Wang, Mujie Li, Xin Wu, Dawei He
Format: Article
Language:English
Published: BMC 2023-11-01
Series:European Journal of Medical Research
Subjects:
piRNAs
piRNA-MW557525
Neuroblastoma
P53
Cell cycle
Online Access:https://doi.org/10.1186/s40001-023-01493-w

Internet

https://doi.org/10.1186/s40001-023-01493-w

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