Human Neutrophil Alpha-Defensins Promote NETosis and Liver Injury in Alcohol-Related Liver Cirrhosis: Potential Therapeutic Agents

Human Neutrophil Alpha-Defensins Promote NETosis and Liver Injury in Alcohol-Related Liver Cirrhosis: Potential Therapeutic Agents

<b>Background</b>: Neutrophils are thought to play a pivotal role in the pathogenesis of many inflammatory diseases, such as hepatitis, liver cirrhosis, etc. Activated human neutrophils release human neutrophil peptides (HNP1-3) or alpha-defensins that are antimicrobial peptides in azuro...

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Bibliographic Details
Main Authors: Anna Rycyk-Bojarzyńska, Beata Kasztelan-Szczerbińska, Halina Cichoż-Lach, Agata Surdacka, Jacek Roliński
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Clinical Medicine
Subjects:
alpha-defensins
human neutrophil peptides (HNPs)
neutrophils
NETosis
neutrophil extracellular trap (NET)
alcohol-related liver cirrhosis
Online Access:https://www.mdpi.com/2077-0383/13/5/1237

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https://www.mdpi.com/2077-0383/13/5/1237

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