Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway

Protective Effect of Glutathione against Oxidative Stress-induced Cytotoxicity in RAW 264.7 Macrophages through Activating the Nuclear Factor Erythroid 2-Related Factor-2/Heme Oxygenase-1 Pathway

Reactive oxygen species (ROS), products of oxidative stress, contribute to the initiation and progression of the pathogenesis of various diseases. Glutathione is a major antioxidant that can help prevent the process through the removal of ROS. The aim of this study was to evaluate the protective eff...

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Bibliographic Details
Main Authors: Da Hye Kwon, Hee-Jae Cha, Hyesook Lee, Su-Hyun Hong, Cheol Park, Shin-Hyung Park, Gi-Young Kim, Suhkmann Kim, Heui-Soo Kim, Hye-Jin Hwang, Yung Hyun Choi
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Antioxidants
Subjects:
glutathione
oxidative stress
DNA damage
apoptosis
ROS
Nrf2/HO-1
Online Access:https://www.mdpi.com/2076-3921/8/4/82

Internet

https://www.mdpi.com/2076-3921/8/4/82

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