Cardiac cell type-specific responses to injury and contributions to heart regeneration

Abstract Heart disease is the leading cause of mortality worldwide. Due to the limited proliferation rate of mature cardiomyocytes, adult mammalian hearts are unable to regenerate damaged cardiac muscle following injury. Instead, injured area is replaced by fibrotic scar tissue, which may lead to ir...

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Bibliographic Details
Main Authors: Weijia Zhang, Jinxiu Liang, Peidong Han
Format: Article
Language:English
Published: SpringerOpen 2021-02-01
Series:Cell Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s13619-020-00065-1