Cardiac cell type-specific responses to injury and contributions to heart regeneration
Abstract Heart disease is the leading cause of mortality worldwide. Due to the limited proliferation rate of mature cardiomyocytes, adult mammalian hearts are unable to regenerate damaged cardiac muscle following injury. Instead, injured area is replaced by fibrotic scar tissue, which may lead to ir...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2021-02-01
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Series: | Cell Regeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13619-020-00065-1 |