In Vivo and In Vitro Study on the Efficacy of Terpinen-4-ol in Dextran Sulfate Sodium-Induced Mice Experimental Colitis

In Vivo and In Vitro Study on the Efficacy of Terpinen-4-ol in Dextran Sulfate Sodium-Induced Mice Experimental Colitis

The purpose of this study was to investigate the protective effects of Terpinen-4-ol (TER) on dextran sulfate sodium (DSS)-induced experimental colitis and clarify the possible mechanisms. In vivo, an acute colitis model was used to confirm the anti-inflammatory activity and the possible mechanisms...

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Bibliographic Details
Main Authors: Zecai Zhang, Peng Shen, Xiaojie Lu, Yanxin Li, Jiuxi Liu, Bo Liu, Yunhe Fu, Yongguo Cao, Naisheng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
terpinen-4-ol
colitis
NLRP3 inflammasome
interleukin-1β
intestinal microbiota
intestinal barrier
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00558/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00558/full

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