Role of TET1-mediated epigenetic modulation in Alzheimer's disease

Role of TET1-mediated epigenetic modulation in Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disorder influenced by a complex interplay of environmental, epigenetic, and genetic factors. DNA methylation (5mC) and hydroxymethylation (5hmC) are DNA modifications that serve as tissue-specific and temporal regulators of gene expression. TET f...

Full description

Bibliographic Details
Main Authors: Matthew J. Armstrong, Yulin Jin, Selina M. Vattathil, Yanting Huang, Jason P. Schroeder, David A. Bennet, Zhaohui S. Qin, Thomas S. Wingo, Peng Jin
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Neurobiology of Disease
Subjects:
5-hydroxymethylcytosine
Alzheimer's disease
Tet1 protein
Gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123002723

Internet

http://www.sciencedirect.com/science/article/pii/S0969996123002723

Similar Items