OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems

Abstract Biomechanical cues from the extracellular matrix (ECM) are essential for directing many cellular processes, from normal development and repair, to disease progression. To better understand cell-matrix interactions, we have developed a new instrument named ‘OptoRheo’ that combines light shee...

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Bibliographic Details
Main Authors: Tania Mendonca, Katarzyna Lis-Slimak, Andrew B. Matheson, Matthew G. Smith, Akosua B. Anane-Adjei, Jennifer C. Ashworth, Robert Cavanagh, Lynn Paterson, Paul A. Dalgarno, Cameron Alexander, Manlio Tassieri, Catherine L. R. Merry, Amanda J. Wright
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04780-8