Macromolecules in polysorbate 80 for injection: an important cause of anaphylactoid reactions

Macromolecules in polysorbate 80 for injection: an important cause of anaphylactoid reactions

Abstract Polysorbate 80 for injection (TW80) is a common excipient used for injection whose macromolecular impurities, including those that cause anaphylactoid reactions, are frequently ignored. The main aim of this study was to prove that the macromolecular impurities in the excipient are an import...

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Bibliographic Details
Main Authors: Yue Li, Jinlian Duan, Heng Xia, Yongkun Li, Bin Shu, Weigang Duan
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Polysorbate 80 for injection
Anaphylactoid reactions
Macromolecular impurities
Capillary permeability
Passive cutaneous anaphylactoid reaction
Online Access:https://doi.org/10.1186/s40360-022-00591-5

Internet

https://doi.org/10.1186/s40360-022-00591-5

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