lon Deletion Impairs Persister Cell Resuscitation in Escherichia coli

ABSTRACT Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However, this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP-dependent protease, has repeatedly been shown to play a critical role in fluoroquinolone persistence in Esc...

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Bibliographic Details
Main Authors: Sayed Golam Mohiuddin, Aslan Massahi, Mehmet A. Orman
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.02187-21