lon Deletion Impairs Persister Cell Resuscitation in Escherichia coli
ABSTRACT Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However, this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP-dependent protease, has repeatedly been shown to play a critical role in fluoroquinolone persistence in Esc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2022-02-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mbio.02187-21 |