Novel 1, 2, 3-triazolic compounds derived from cytosine: Synthesis, spectroscopic characterization, in vitro antimicrobial activity and molecular docking studies

Novel 1, 2, 3-triazolic compounds derived from cytosine: Synthesis, spectroscopic characterization, in vitro antimicrobial activity and molecular docking studies

The development of novel antimicrobial drugs is crucial due to the increasing problem of antibiotic resistance. A new series of 1,4-disubstituted-1,2,3-triazole derivatives containing a cytosine moiety (3a, 3b, 3c and 3d) were synthesized using 1,3-dipolar cycloaddition in a mixture of ethanol and w...

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Bibliographic Details
Main Authors: Mouad Lahyaoui, Riham Sghyar, Khadija Benamar, Mouad Filali, Kawtar Fikri-Benbrahim, Badr Eddine Kartah, Ahmed Mazzah, Youssef Kandri Rodi, Nada Kheira Sebbar
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Cycloaddition
Triazoles
Cytosine
Antimicrobial activity
Docking studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624001061

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http://www.sciencedirect.com/science/article/pii/S2211715624001061

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