The Intersection of Purine and Mitochondrial Metabolism in Cancer

The Intersection of Purine and Mitochondrial Metabolism in Cancer

Nucleotides are essential to cell growth and survival, providing cells with building blocks for DNA and RNA, energy carriers, and cofactors. Mitochondria have a critical role in the production of intracellular ATP and participate in the generation of intermediates necessary for biosynthesis of macro...

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Bibliographic Details
Main Authors: Humberto De Vitto, Danushka B. Arachchige, Brian C. Richardson, Jarrod B. French
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
purines
mitochondrial metabolism
amino acids
metabolic reprogramming
cancers
Online Access:https://www.mdpi.com/2073-4409/10/10/2603

Internet

https://www.mdpi.com/2073-4409/10/10/2603

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