Pathophysiology of Type 2 Diabetes Mellitus

Pathophysiology of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Because insulin release and activity a...

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Bibliographic Details
Main Authors: Unai Galicia-Garcia, Asier Benito-Vicente, Shifa Jebari, Asier Larrea-Sebal, Haziq Siddiqi, Kepa B. Uribe, Helena Ostolaza, César Martín
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
type 2 diabetes mellitus
insulin resistance
β-cell
liver
adipocyte
muscle
Online Access:https://www.mdpi.com/1422-0067/21/17/6275

Internet

https://www.mdpi.com/1422-0067/21/17/6275

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