Bioresponsive and immunotherapeutic nanomaterials to remodel tumor microenvironment for enhanced immune checkpoint blockade

Immune checkpoint blockade (ICB) therapy is a revolutionary approach to treat cancers, but still have limited clinical applications. Accumulating evidence pinpoints the immunosuppressive characteristics of the tumor microenvironment (TME) as one major obstacle. The TME, characterized by acidity, hyp...

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Bibliographic Details
Main Authors: Tianxu Fang, Xiaona Cao, Li Wang, Mo Chen, Yueyang Deng, Guojun Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-02-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23003389