Metabolically stable bradykinin B2 receptor agonists enhance transvascular drug delivery into malignant brain tumors by increasing drug half-life

<p>Abstract</p> <p>Background</p> <p>The intravenous co-infusion of labradimil, a metabolically stable bradykinin B2 receptor agonist, has been shown to temporarily enhance the transvascular delivery of small chemotherapy drugs, such as carboplatin, across the blood-bra...

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Bibliographic Details
Main Authors: Glen Daniel, Cox Robert W, Butman John A, Fung Steve H, Kanevsky Ariel S, Sarin Hemant, Reynolds Richard, Auh Sungyoung
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/7/1/33