MIR124-3 and NKX6-1 hypermethylation profiles accurately predict metachronous gastric lesions in a Caucasian population

MIR124-3 and NKX6-1 hypermethylation profiles accurately predict metachronous gastric lesions in a Caucasian population

Abstract Background Early gastric cancer is treated endoscopically, but patients require surveillance due to the risk of metachronous gastric lesions (MGLs). Epigenetic alterations, particularly aberrant DNA methylation in genes, such as MIR124-3, MIR34b/c, NKX6-1, EMX1, MOS and CDO1, have been iden...

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Bibliographic Details
Main Authors: Catarina Lopes, Tatiana C. Almeida, Catarina Macedo-Silva, João Costa, Sofia Paulino, Carmen Jerónimo, Diogo Libânio, Mário Dinis-Ribeiro, Carina Pereira
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Clinical Epigenetics
Subjects:
Gastric cancer
Epigenetics
MicroRNAs
Molecular markers
Precision medicine
Online Access:https://doi.org/10.1186/s13148-024-01712-z

Internet

https://doi.org/10.1186/s13148-024-01712-z

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