BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy

Abstract Background Inflammation and apoptosis of chondrocytes are the pathological bases of osteoarthritis. Autophagy could alleviate the symptoms of inflammation and apoptosis. Previous study has shown that BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) can induce the occurrence...

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Bibliographic Details
Main Authors: Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang, Yuanshi Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Autophagy
BNIP3
Chondrocytes
Inflammation
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13018-020-01791-7

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http://link.springer.com/article/10.1186/s13018-020-01791-7

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