Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors

<p>Abstract</p> <p>Background</p> <p>Surrogate measures for cardiovascular disease events have the potential to increase greatly the efficiency of clinical trials. A leading candidate for such a surrogate is the progression of intima-media thickness (IMT) of the carotid...

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Bibliographic Details
Main Authors: Morgan Timothy, Terry James G, O'Leary Daniel H, Espeland Mark A, Evans Greg, Mudra Harald
Format: Article
Language:English
Published: BMC 2005-03-01
Series:Current Controlled Trials in Cardiovascular Medicine
Subjects:
Online Access:http://cvm.controlled-trials.com/content/6/1/3