Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors

Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors

<p>Abstract</p> <p>Background</p> <p>Surrogate measures for cardiovascular disease events have the potential to increase greatly the efficiency of clinical trials. A leading candidate for such a surrogate is the progression of intima-media thickness (IMT) of the carotid...

Full description

Bibliographic Details
Main Authors:	Morgan Timothy, Terry James G, O'Leary Daniel H, Espeland Mark A, Evans Greg, Mudra Harald
Format:	Article
Language:	English
Published:	BMC 2005-03-01
Series:	Current Controlled Trials in Cardiovascular Medicine
Subjects:	Arteriosclerosis carotid arteries drugs meta-analysis statistics ultrasonics
Online Access:	http://cvm.controlled-trials.com/content/6/1/3

Similar Items

Blood flow analysis in carotid artery bifurcation by two-dimensional ultrasonic-measurement-integrated simulation
by: Hiroko KADOWAKI, et al.
Published: (2014-09-01)

HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection
by: Vamvakopoulos Joannis E, et al.
Published: (2003-07-01)

Historical overview of carotid artery surgical treatment
by: Popov Petar, et al.
Published: (2008-01-01)

Atherosclerotic plaque in carotid arteries in systemic lupus erythematosus: frequency and associated risk factors
by: Alexandre Wagner Silva de Souza, et al.

Correlation between significant asymptomatic carotid artery stenosis and severity of peripheral arterial occlusive disease in the lower limb: a retrospective study on 200 patients
by: Zhongjie Pan, et al.
Published: (2019-10-01)

Study on the correlation between carotid artery lesion and fundus arteriosclerosis in patients with cerebral infarction
by: Wei-Qiong Song, et al.
Published: (2017-11-01)

The dynamics of blood pressure within 12 months after carotid artery stenting in patients with stenotic carotid lesions
by: F. B. Shukurov, et al.
Published: (2019-09-01)

The Correlation Between Collagen Types and Ultrasound Feature Score in Evaluating the Vulnerability of Carotid Artery Plaque
by: Ruijun Han, et al.
Published: (2021-11-01)

Corrigendum: The correlation between collagen types and ultrasound feature score in evaluating the vulnerability of carotid artery plaque
by: Ruijun Han, et al.
Published: (2023-03-01)

Effect of fosinopril on progression of the asymptomatic carotid atherosclerosis and left ventricular hypertrophy in hypertensive patients
by: Tasić Ivan, et al.
Published: (2006-01-01)

An improvement of carotid intima-media thickness and pulse wave velocity in renal transplant recipients
by: Zhaojun Li, et al.
Published: (2018-08-01)

Prediction of Hemodynamic-Related Hemolysis in Carotid Stenosis and Aiding in Treatment Planning and Risk Stratification Using Computational Fluid Dynamics
by: Krystian Jędrzejczak, et al.
Published: (2023-12-01)

Carotid ultrasonographic parameters as markers of atherogenesis and mortality rate in patients on hemodialysis
by: Stolić Radojica, et al.
Published: (2010-01-01)

Effect of rosuvastatin on inflammatory factors and carotid atherosclerotic plaque in patients with acute ischemic stroke
by: Jun YAN, et al.
Published: (2013-10-01)

Clinical value of right subclavian artery atheromatosis presented as the marker of early carotid artery arteriosclerosis
by: Pan CHENG, et al.
Published: (2013-04-01)

Network of Interactions Between Gut Microbiome, Host Biomarkers, and Urine Metabolome in Carotid Atherosclerosis
by: Rui-Jun Li, et al.
Published: (2021-10-01)

Assessment of hemodynamic changes near carotid atherosclerotic plaques by using magnetic resonance imaging and computational fluid dynamics
by: Li-na JING, et al.
Published: (2014-07-01)

HMG CoA reductase inhibitors in the treatment of hypercholesterolaemias.
by: Aronson, J, et al.
Published: (1990)

Pleiotropic effects of the HMG-CoA reductase inhibitors
by: Mihos CG, et al.
Published: (2011-04-01)

The discovery and development of HMG-CoA reductase inhibitors.
by: A Endo
Published: (1992-11-01)

Extracranial carotid artery atherosclerotic plaque and APOE polymorphisms: a systematic review and meta-analysis
by: Sinéad Culleton, et al.
Published: (2023-11-01)

Circulating de novo Donor Specific Antibodies and Carotid Intima-media Thickness in Pediatric Kidney Transplant Recipients, A Pilot Study
by: Kristen Sgambat, et al.
Published: (2020-01-01)

HMG CoA reductase of intestinal mucosa and liver of the rat
by: S. Shefer, et al.
Published: (1972-05-01)

HMG-CoA reductase is not the site of the primary defect in phytosterolemia
by: G.M.B. Berger, et al.
Published: (1998-05-01)

The trend in the changing of human peripheral blood endothelial progenitor cells after brain infarction due to carotid atherosclerosis
by: Rong⁃dong NIU, et al.
Published: (2010-12-01)

Sensitivity of hemodynamic parameters obtained by conventional duplex scanner in the evaluation of extracranial carotid disease severity
by: Aranđelović-Minić Gordana
Published: (2003-01-01)

Eupatilin Alleviates Hyperlipidemia in Mice by Inhibiting HMG-CoA Reductase
by: Kyung-Joo Kim, et al.
Published: (2023-01-01)

The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation
by: Paolo Gelosa, et al.
Published: (2007-11-01)

Measurement of human leukocyte microsomal HMG-CoA reductase activity.
by: H J Harwood, Jr, et al.
Published: (1984-09-01)

Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol
by: R Langdon, et al.
Published: (1977-01-01)

Diurnal variation of HMG CoA reductase activity in rat intestine
by: S. Shefer, et al.
Published: (1972-09-01)

Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
by: Noel Lorenzo Villalba, et al.
Published: (2021-06-01)

Carotid atherosclerosis detectability in patients with coronary heart diseaseand arterial hypertension
by: I A Astanina, et al.
Published: (2004-12-01)

Correlation analysis between the carotid artery atherosclerosis severity of patients with lacunar infarct and the level of serum uric acid, high-sensitivity C-reactive protein
by: Shu WANG
Published: (2013-01-01)

Correlation between asymptomatic intracranial arterial stenosis and carotid atherosclerosis in patients with Type 2 diabetes mellitus
by: Yang SONG, et al.
Published: (2010-06-01)

Sex-specific association between carotid atherosclerosis and fundus arteriosclerosis in a Chinese population: a retrospective cross-sectional study
by: Chunxing Liu, et al.
Published: (2023-11-01)

Ultrasound Diagnosis of Hepatic Steatosis as a Surrogate for Atherosclerosis
by: S. Guth, et al.
Published: (2016-03-01)

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
by: Marc M Schumacher, et al.
Published: (2015-03-01)

Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression.
by: JJ Hwa, et al.
Published: (1992-05-01)

Inactivation of rat liver HMG-CoA reductase phosphatases by polycarboxylic acids.
by: F G Hegardt, et al.
Published: (1983-07-01)