Global renal gene expression profiling analysis in B2-kinin receptor null mice: impact of diabetes.

Diabetic nephropathy (DN), the leading cause of end-stage renal failure, is clinically manifested by albuminuria and a progressive decline in glomerular filtration rate. The risk factors and mechanisms that contribute to the development and progression of DN are still incompletely defined. To addres...

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Bibliographic Details
Main Authors: Miran A Jaffa, Firas Kobeissy, Moustafa Al Hariri, Hussein Chalhoub, Assaad Eid, Fuad N Ziyadeh, Ayad A Jaffa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3445541?pdf=render