UPR-Induced miR-616 Inhibits Human Breast Cancer Cell Growth and Migration by Targeting c-MYC

UPR-Induced miR-616 Inhibits Human Breast Cancer Cell Growth and Migration by Targeting c-MYC

C/EBP homologous protein (CHOP), also known as growth arrest and DNA damage-inducible protein 153 (GADD153), belongs to the CCAAT/enhancer-binding protein (C/EBP) family. CHOP expression is induced by unfolded protein response (UPR), and sustained CHOP activation acts as a pivotal trigger for ER str...

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Bibliographic Details
Main Authors: Vahid Arabkari, Afrin Sultana, David Barua, Mark Webber, Terry Smith, Ananya Gupta, Sanjeev Gupta
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
unfolded protein response
ER stress
miR-616
c-MYC
breast cancer
Online Access:https://www.mdpi.com/1422-0067/24/17/13034

Internet

https://www.mdpi.com/1422-0067/24/17/13034

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