In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells
Abstract To enter mitosis, most adherent animal cells reduce adhesion, which is followed by cell rounding. How mitotic cells regulate adhesion to neighboring cells and extracellular matrix (ECM) proteins is poorly understood. Here we report that, similar to interphase, mitotic cells can employ integ...
Main Authors: | Maximilian Huber, Javier Casares-Arias, Reinhard Fässler, Daniel J. Müller, Nico Strohmeyer |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-37760-x |
Similar Items
-
αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin
by: Mitasha Bharadwaj, et al.
Published: (2017-01-01) -
Integrin-Mediated Adhesion Promotes Centrosome Separation in Early Mitosis
by: Siamak A. Kamranvar, et al.
Published: (2022-04-01) -
Reciprocal discoidin domain receptor signaling strengthens integrin adhesion to connect adjacent tissues
by: Kieop Park, et al.
Published: (2023-07-01) -
The Potential of Extracellular Matrix- and Integrin Adhesion Complex-Related Molecules for Prostate Cancer Biomarker Discovery
by: Ivana Samaržija
Published: (2023-12-01) -
Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion
by: Lisa S. Fischer, et al.
Published: (2021-02-01)