Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production

Curcuminoids and ω-3 fatty acids with anti-oxidants potentiate cytotoxicity of natural killer cells against pancreatic ductal adenocarcinoma cells and inhibit interferon γ production

Pancreatic cancer has a poor prognosis attributed in part to immune suppression and deactivation of natural killer (NK) cells. Curcuminoids have a potential for improving the therapy of pancreatic cancer given promising results in cancer models and a clinical trial, but their oral absorption is limi...

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Bibliographic Details
Main Authors: Milan eFiala, Ramesh eHalder, Anasheh eAlmasi, Bien eSagong, Jessica eLeung, Anahid eJewett
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Physiology
Subjects:
Curcumin
Pancreatic Cancer
Natural Killer cells
Interferon-γ
ω-3 fatty acids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00129/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00129/full

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