Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling

Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling

Haloalkane dehalogenases are enzymes that catalyze the cleavage of carbon-halogen bonds in halogenated compounds. They serve as model enzymes for studying structure–function relationships of >100.000 members of the α/β-hydrolase superfamily. Detailed kinetic analysis of their reaction is crucial...

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Bibliographic Details
Main Authors: Veronika Dockalova, Esther M. Sanchez-Carnerero, Zuzana Dunajova, Eduardo Palao, Michaela Slanska, Tomas Buryska, Jiri Damborsky, Petr Klán, Zbynek Prokop
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Haloalkane dehalogenase
Fluorescent substrate
Enzyme kinetics
Mechanism
Protein labeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019305665

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http://www.sciencedirect.com/science/article/pii/S2001037019305665

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