AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity

AIM2 promotes TH17 cells differentiation by regulating RORγt transcription activity

Summary: AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA sensor. Recent studies have highlighted AIM2’s function on regulatory T cells (Treg) and follicular T cells (Tfh). However, its involvement in Th17 cell dif...

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Bibliographic Details
Main Authors: Jefferson Antônio Leite, Luísa Menezes, Eloisa Martins, Tamara Silva Rodrigues, Lucas Tavares, Anna Ebering, Carsten Schelmbauer, Guilherme C. Martelossi Cebinelli, Valeriya Zinina, Artemiy Golden, Natalia Soshnikova, Dario S. Zamboni, Fernando Q. Cunha, Magdalena Huber, João Santana Silva, Ari Waisman, Daniela Carlos, Niels Olsen Saraiva Câmara
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Biological sciences
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223022113

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223022113

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