Enrofloxacin and Toltrazuril Are Able to Reduce Toxoplasma gondii Growth in Human BeWo Trophoblastic Cells and Villous Explants from Human Third Trimester Pregnancy

Enrofloxacin and Toltrazuril Are Able to Reduce Toxoplasma gondii Growth in Human BeWo Trophoblastic Cells and Villous Explants from Human Third Trimester Pregnancy

Classical treatment for congenital toxoplasmosis is based on combination of sulfadiazine and pyrimethamine plus folinic acid. Due to teratogenic effects and bone marrow suppression caused by pyrimethamine, the establishment of new therapeutic strategies is indispensable to minimize the side effects...

Full description

Bibliographic Details
Main Authors: Rafaela J. da Silva, Angelica O. Gomes, Priscila S. Franco, Ariane S. Pereira, Iliana C. B. Milian, Mayara Ribeiro, Paolo Fiorenzani, Maria C. dos Santos, José R. Mineo, Neide M. da Silva, Eloisa A. V. Ferro, Bellisa de Freitas Barbosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Toxoplasma gondii
trophoblast
placenta
enrofloxacin
toltrazuril
treatment
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00340/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00340/full

Similar Items