Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN)

Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN)

Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC), can be challenging, as features of dVIN may mimic those of non-dysplastic dermatoses. To aid the diagnosis, p53-immunohisto...

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Bibliographic Details
Main Authors: Shatavisha Dasgupta, Senada Koljenović, Thierry P. P. van den Bosch, Sigrid M. A. Swagemakers, Nick M. A. van der Hoeven, Ronald van Marion, Peter J. van der Spek, Helena C. van Doorn, Folkert J. van Kemenade, Patricia C. Ewing-Graham
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
vulva
keratin-17
SOX2 protein, human
carcinoma-in-situ
neoplasms, squamous cell neoplasm
Online Access:https://www.mdpi.com/1424-8247/14/4/324

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https://www.mdpi.com/1424-8247/14/4/324

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